Intrathoracic Meningocele and Neurofibromatosis

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Intrathoracic meningocele. Its development and association with neurofibromatosis.

An antero-lateral meningocele is a protrusion of the spinal meninges through an intervertebral foramen. It contains an extension of the subarachnoid space, filled with cerebrospinal fluid, and this gives rise to a paravertebral cystic swelling, usually spherical in shape. Theoretically such a swelling could occur in the neck, or in the thoracic, abdominal, or pelvic cavities, but practically al...

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A Large Intrathoracic Meningocele in a Patient with Neurofibromatosis-1

A large intrathoracic meningocele, a saccular protrusion of the meninges through a dilated intervertebral foramen or a bony defect of the vertebral column, was diagnosed in a 41-year-old female patient showing clinical features of neurofibromatosis-1 (NF-1), including café-au-lait spots, cutaneous neurofibromas, and axillary frecklings and Lisch nodules on the iris. Her daughter and son also ha...

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Diagnosis of intrathoracic meningocele.

Intrathoracic meningocele is looked upon by many as a rare tumor of the thoracic cavity. Its diagnosis is usually not made preoperatively. Among the twenty-odd certain cases reported in the literature there are no more than 4 diagnosed with certainty without thoracotomy (SchUller and Uiberall 1938, Head 1949, Cross and co-workers 1949, Cmyral 1952, and Scars, Clayton and Siebel 1953) ; to these...

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Massive Spontaneous Hemothorax, Giant Intrathoracic Meningocele, and Kyphoscoliosis in Neurofibromatosis Type 1

Neurofibromatosis type 1 (NF-1) is a heterogeneous autosomal dominant disease with an incidence ranging from 1 in 2500 to 1 in 3000. Rare intrathoracic vascular disorders resulting in massive spontaneous hemothorax with fatal consequences may occur in these patients, so also are various types of skeletal dysplasia which may result in dramatic presentations, posing management challenges to the a...

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Intrathoracic meningoceles are relatively rare entities found in patients with neurofibromatosis type I (NF1). Given that both the BRCA1 and NF-1 genes are located on the same long arm of chromosome 17, one would expect concurrence of neurofibromatosis and breast cancer. However, incidence of such co-disorders is very rare in the literature. Here, the authors report a case of a 50-year-old fema...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society of Medicine

سال: 1966

ISSN: 0035-9157

DOI: 10.1177/003591576605900631